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Although no considerable differences had been found in tyrosine hydroxylase action and expression, Mind tissue levels of three,four-dihydroxyphenylalanine were threefold greater in α2A- and α2C-adrenoceptor KO mice. Brain tissue levels of dopamine and noradrenaline were considerably bigger in α2A and α2CKOs in comparison with WT [WT: two.Addiso